The key ingredient is AglyMax®, containing isoflavone aglycones. Isoflavone aglycones are only found in fermented soy, like miso, a Japanese staple.
Try natural ingredients that are little known in the USA.
Over 180,000 supplements have been sold and prescribed at more than 200 women's health support centers in Japan.
EFFISOY® is the only supplement containing AglyMax® available in the USA and Outside Japan
What is AglyMax®?
Statistics and research show that Japanese women have far easier menopause experiences, a much lower risk of breast cancer onset, and long life expectancy .
One of the secrets of this is said to be miso. Miso paste is fermented soy and most Japanese people eat miso soup every day.
Standard isoflavones (isoflavone glycosides) are structurally related to sugar with a molecular size that is too large to be absorbed as they are by the gut. Enteric bacteria remove this sugar and make it absorbable, but only partly. However, fermentation totally removes the sugar so isoflavones from fermented soy (isoflavoen aglycones) can be absorbed fully.
One of the major Japanese food manufacturing enterprises, Nichimo, made a compound extracted from fermented soy bean germ, which contains concentrates isoflavone aglycones. This supplement ingredient was named AglyMax®.
Is AglyMax® Popular?
Yes. If you search for "AglyMax" on Google, Bing or another search engine, you will find a lot of pages in Japanese as well as a number of clinical reports in English.
One supplement containing AglyMax® has sold over 180,000 bottles in Japan. One doctor's supplement with AglyMax® is prescribed at over 200 women's health support centers, also in Japan.
AglyMax® is also known to improve implanation ratio in fertility treatments and is prescribed by many fertility doctors in Japan.
How Does AglyMax® Work?
DHEA is an estrogen precursor. Synthesis capacity of DHEA wanes with age. AglyMax® was proven to enhance the natural synthesis ability of DHEA inside the human body.
Is the concept of AglyMax® the same as DHEA supplements?
No, it is totally different. DHEA supplementation aims to supplement
DHEA externally and expects it to be turned into estrogen. The idea is similar to hormone replacement therapy but without a doctor's prescription. Human hormones have a very fine balance in quantity. Such self-balancing of hormones can easily cause excessive estrogen, and often leads to the over-synthesis of androgens (male hormones)
The table above shows the changes in the quantity of estrogens and DHEA (mostly existing as DHEA-S in the body) after isoflavone aglycone supplementation. You can see that DHEA is significantly increased within a few months. It is through your natural adjustment from within.
Though DHEA is naturally increased, doesn't it eventually have the same effect as DHEA supplements?
Not at all. In the same table, you can see that the 3 estrogens are not meaningfully increased while DHEA is almost tripled. AglyMax® is proven to suppress the enzyme that turns DHEA into estrogen (and it also causes an increase in DHEA).
If estrogen is not increased, how can it rebalance my hormones?
DHEA is a precursor of estrogen, but it doesn't have the power of estrogen.
When estrogen decreases due to aging, some estrogen receptors become vacant, which causes menopausal symptoms. However, the vacant estrogen receptors do not necessarily need to be filled with estrogen.
Even weaker or milder replacements can also fill the vacant estrogen receptors. Safe replacement like DHEA rear will not turn into estrogen will fill the vacancy and rebalance your hormones without causing any side effects due to excessive estrogen.
AglyMax® also works as isoflavones, as it can be fully absorbed. Isoflavones have about 1/1,000 - 1/10,000 the power of estrogen. Isoflavones also fill vacant estrogen receptors quite safely with their almost negligible power as phytoestrogen.
Are soy and isoflavone safe?
This is one of the most common questions in the USA, but it sounds somehow weird to Japanese people who consume a lot of soy in various ways every day as part of their traditional diet. Japanese people are known to enjoy above average health. We found some online resources claiming the risk of isoflavones only as online news articles or blogs.
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Their common arguments are, "estrogen is a phytoestrogen, so isoflavones may prompt or stimulate breast cancer," and "they are not clinically confirmed yet."
All of these arguments lack the view that estrogen has negligible power as a phytoestrogen and neglect to acknowledge that Japanese people, who consume a lot of soy every day, are among the healthiest people in the world.
In the last decade, "protective effect" of isoflavones have become well known in Japan. Isoflavones protect the estrogen receptors from excessive estrogen stimulation because such powerless isoflavones replace estrogen in the estrogen receptors. This is mostly confirmed by a large-scale cohort study by the National Cancer Center of Japan and Western institutes have also been confirming it in the last decade.
Japanese eat a lot of soy per capita, the far top above the 2nd, while Americans eat almost no soy.
The following is a summery of the large-scale cohort study by the National Cancer Center of Japan mentioned above, just for your reference. ( We are simply introducing their study already in public and we are not in a position to determine any medical facts.)
A huge cohort study, conducted by the National Cancer Center of Japan, followed 20,000 women, aged 44-59, for 10 years. The study aimed to find a correlation between consumption of soy-based foods and the risk of breast cancer.
Charts show that a diet high in isoflavones decreases the onset ratio of breast cancer. A diet high in miso soup has the strongest negative correlation with risk of breast cancer.
The reason is now clear: Miso soup contains isoflavone aglycones, which are easily absorbabed and stimulate the body’s natural systems.
(Please note that we are simply introducing a study to the public, but are not in a position to determine any medical facts.)
